INS and COVID-19: Furthermore, in relation to the staging of COVID-19 and the clinical outcome, it was observed that patients undergoing treatment with insulin had a higher severity of the disease with three deaths, compared to a lower severity of the disease and to 0 deaths for the group of patients on metformin treatment (OR for severe COVID-19: 0.8, 95 CI (0.6–0.9) metformin treatment vs. no metformin treatment; p: 0.042 and OR for death: 1.1, 95 CI (0.84–1.15) metformin treatment vs. no metformin treatment; p: 0.072).