One study in patients with MetS reported an increased number of myeloid dendritic cells and decreased monocyte expression of inflammatory cytokines [(tumor necrosis factor (TNF) and interleukin (IL)-6], toll-like receptor 4, and serum granulocyte-macrophage colony-stimulating factor in the BB group (vs. controls) [22]. The gene discussed is TLR4; the disease is metabolic syndrome.