Gene expressions of Spp1 and 9 NASH/HCC biomarkers (Fas, Cd36, Ppara, Pparg, Fgf21, Cmyc, Ctnnb1, Ki67, and Tert) were quantified from obese, post-BS and -Diet mouse livers. Here, FGF21 is linked to metabolic dysfunction-associated steatohepatitis.