SPP1 and metabolic dysfunction-associated steatohepatitis: The match-up analysis was conducted from the “MEtan” module by WGCNA, upregulated DEGs in NASH-HCC dataset, and downregulated DEGs in the BS group, generating 7 overlapping genes (MNDA, ALOX5AP, PECAM1, SPP1, CD86, FGF21, CSTA) (Figure 4E).