Out of the three monocyte subsets investigated (classical, intermediate, and non-classical) and their MPAs, intermediate monocytes (CD14++CD16+) and their MPAs were the only predictors for MACE after a 2-year follow-up (CV death, recurrent MI, HF hospitalization, emergency or repeat vascularization, or nonfatal ischemic stroke) [31]. The gene discussed is CD14; the disease is ischemic stroke.