Lazurova et al. demonstrated that PCOS women with high-BPA levels had significantly higher serum insulin and Homeostatic Model Assessment for Insulin Resistance (HOMA IR) compared to low-BPA PCOS women, with no significant difference in body mass index (BMI) among both groups [91], similarly to Kandaraki et al. and Tarantino et al. [89,94]. This evidence concerns the gene INS and polycystic ovary syndrome.