MALAT1 and early-onset autosomal dominant Alzheimer disease: Likewise, the abundant lncRNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), also known as NEAT2, binds with a specific set of mRNA-processing proteins to form nuclear splicing speckles and interacts with miR-125b to inhibit neuronal apoptosis and suppress inflammatory cytokines in Alzheimer’s disease [8,9].