The third most frequent AE was hepatotoxicity, with more cases of hypertransaminasemia (mean aspartate aminotransferase (AST), 62.7 (SD 21.2) IU/L and alanine aminotransferase (ALT), 92.1 (SD 42.2) IU/L) than of hyperbilirubinemia (mean bilirubin, 24.9 (SD 14.4) μmol/L). The gene discussed is GPT; the disease is Hyperbilirubinemia.