The forest plot drawn by the subsequent univariate Cox regression analysis showed that genes such as HSP90AA1, PANX1, BNIP3, FLT3, SLC39A7, TNFRSF1B, CD40, IPMK, PLK1, HSPA4, FASLG, LEF1, and IDH2 play a critical role in the progression of breast cancer (Figure 2B). The gene discussed is TNFRSF1B; the disease is breast cancer.