Ling et al. reported that in 31 CRC patients the levels of circulating Th17 (defined as IL-17+IL-22−IFN-γ−CD4+), Th22 (defined as IL-17−IL-22+IFN-γ−CD4+), and IL-17+IL-22+IFN-γ−CD4+ T cells were higher on POD 14 than before the operation. Here, IL22 is linked to colorectal carcinoma.