We analyzed the correlations between a-STI and age, heart rate, mean artery pressure, gas-exchange, arterial lactate concentration, brain natriuretic peptide (NT-pro BNP), SCr, urinary output, ejection fraction, TAPSE, left ventricular ejection fraction, SOFA score, coronary heart disease, hypertension, or diabetes. This evidence concerns the gene NPPB and hypertensive disorder.