The expression levels of the four model genes were validated in the GSE70768 and GSE55945 datasets, and the results indicated that APOE, DNAH8, and EME2 were significantly lower expressed in PCa samples compared to normal samples, while the expression levels of KIF5A showed no significance between normal and PCa samples (Figure 6). The gene discussed is DNAH8; the disease is posterior cortical atrophy.