KL and chronic kidney disease: A post hoc analysis of a prospective cohort study suggested that the risk of reaching the primary composite outcome of the progression of CKD and death was significantly higher in patients with α-Klotho levels ≤ 396.3 pg/mL than in patients with α-Klotho levels > 396.3 pg/mL (hazard ratio, 2.03; 95% confidence interval, 1.07–3.85; p = 0.03) [19].