The frequencies of homozygous deletions at ETV1 (3.0% vs. 0.1%, p = 0.0037), KMT2C (3.9% vs. 0.19%, p = 0.0076), and FANCA (4.8% vs. 1.17%, p = 0.0499) were nominally higher in MMR-d primary tumors, as were the frequencies of homozygous deletions at EPAS1 (5.7% vs. 0.1%, p = 0.0030) and INHA (5.7% vs. 0.3%, p = 0.0094) in MMR-d metastatic tumors. This evidence concerns the gene FANCA and metastatic neoplasm.