Of note, we found that most studies with Sonoclot® were performed in cardiac surgery (four out of the five retrieved studies); ROTEM® sigma was the only one studied during post-partum hemorrhage (in total, six studies with ROTEM® sigma); TEG® and Quantra® devices were studied five times (across all settings but post-partum hemorrhage and only trauma and cardiac surgery, respectively), whereas ClotPro® was just once, and with the tPA test only (liver transplantation). The gene discussed is PLAT; the disease is hemorrhage.