For example, MYD88-L265P encoding mutations are known to occur in a fraction of the activated B cell (ABC) diffuse large B-cell lymphomas (DLBCL), in the vast majority of LPL, and in rare MZL, with differences based on the primary anatomical site [2,10,11,12,13,14,15,16,17]. This evidence concerns the gene MYD88 and diffuse large B-cell lymphoma.