In addition to the regulation of sodium channels, FGF13 can also regulate other voltage-gated ion channels [53,54] and affects many other physiological and pathological processes, including the regulation of arrhythmia [53], cancer [55], polycystic ovary syndrome [56], smooth muscle and skeletal muscle cell development [57], and inflammatory pain [58]. The gene discussed is FGF13; the disease is polycystic ovary syndrome.