TGFB1 and pulmonary fibrosis: It also can induce FMT in other ways; for example, in TGF-β-induced pulmonary fibrosis, circHIPK3 1 enhances the expression of FOXK2 by competitively binding to miR-30-3p, promoting the glycolysis level of embryonic lung fibroblasts, induces FMT [31] and 2 binds competitively to miR-338-3p, improving the expression of SOX4 and COL1A to induce FMT [32].