In this direction, the importance of glucose transporters in Kras-driven lung adenocarcinomas has been investigated, revealing that in a KrasLSL-G12D/WT;Trp53flox/flox lung adenocarcinoma mouse model concomitant deletion of the glucose transporters Glut1 and Glut3, significantly decreases tumor progression [18]. This evidence concerns the gene KRAS and lung adenocarcinoma.