AKT2 and cancer: This AKT2-siRNA delivery strategy exerted an inhibitory effect on CSC invasion and metastasis.Reduced the percentage of CSCs, limited the formation of mammospheres, suppressed cancer invasiveness, and sensitized cancer cells to DOX-loaded micellar nanoparticles.TV-miR-34a was shown to successfully eliminate CSCs and increase treatments’ efficacy against cancerous tissue when paired with docetaxel [180].