The gene expression levels of CB1R, CB2R, and FZD 7 were evaluated by droplet digital PCR (ddPCR) in the untreated cells (CTR), in the HepaRG cells treated with exosomes derived from healthy subjects (H-EX), and HepaRG cells treated with exosomes derived from NAFLD patients (P-EX). This evidence concerns the gene CNR1 and metabolic dysfunction-associated steatotic liver disease.