CNR1 and metabolic dysfunction-associated steatotic liver disease: The cultured cells treated with exosomes of patients with NAFLD showed a significant increase in CB1R expression compared to the control and to the cells treated with exosomes derived from healthy subjects, both at 24 h and 48 h (Figure 3 Panel A,E, respectively, ANOVA and Tukey post-test, * p < 0.05, ** p < 0.001).