A number of amplifications and losses were observed only in the metastatic tumor and not in the primary tumor; these included amplifications of TGFBR2, CTNNB1 and FHIT on chromosome 3p, amplification of PIK3CA, CBLB, and KALRN on 3q, amplification of FGFR1 on 8p, amplifications of CDK8 on chromosome 13q, and amplification of ERBB2, which encodes HER2 on 17q. Here, ERBB2 is linked to metastatic neoplasm.