In our previous studies on apoE/LDLR−/− mice fed CLA-enriched egg yolks, we observed no significant changes in the amount of atherosclerosis, but we reported the stabilization of the plaque introduced as lower-macrophage accumulation (CD68), and the greater area covered by SMA-positive cells in aortic plaques in CLA-enriched eggs [50]. This evidence concerns the gene SELPLG and atherosclerosis.