We analyzed the clinical database (TCGA and Kaplan–Meier plotter) focusing on the individual prognostic value of the following glycolytic markers for ovarian cancer: (i) SLC2A1 (GLUT1 gene), the carrier responsible for glucose internalization into the cells; (ii) HK2, the key enzyme for the rate-limiting step of glycolysis; and (iii) SLC16A4 (MCT4 gene), the transporter of monocarboxylates mainly involved in the efflux of lactate deriving from glycolysis. This evidence concerns the gene HK2 and ovarian carcinoma.