Using the website tool of Comprehensive Analysis on Multi-Omics of Immunotherapy in pan-cancer (CAMOIP) [17], we found that the frequencies of mutations in several tumor suppressor genes (e.g., TP53 and PTEN) and oncogenes (e.g., CTNNB1) were unequally distributed in the ERFEhigh versus ERFElow groups. The gene discussed is PTEN; the disease is cancer.