CASP3 and nasopharyngeal carcinoma: Results in human nasopharyngeal carcinoma cells (NPC-039 and NPC-BM) provide a significant contribution to the pathways involved when cells are exposed to 80 μM of L-7-G, reporting the reduced expression of anti-apoptotic proteins Bcl-2 and Bcl-xL, and the higher expression of FAS, TNFR1, RIP, DR5, cleaved caspase-3, 8 and -9, Bax, t-BID and cleaved PARP, indicating the involvement of mitochondria in the apoptosis [158].