GREM2 and Oligodontia: To date, only seven genes (MSX1, OMIM #106600; PAX9, OMIM #604625; EDA, OMIM #313500; WNT10A, OMIM #150400; LRP6, OMIM #616724; WNT10B, OMIM #617073; and GREM2, OMIM #617275) have been confirmed as causative factors associated with nonsyndromic oligodontia [3,4,5,6,7,8,9] and there is evidence to support the candidacy of seven genes (AXIN2, EDAR, EDARADD, DKK1, BMP2, BMP4, and KDF1) that may play a role in nonsyndromic oligodontia [10].