NPM1 and acute myeloid leukemia: To identify the dysregulated autophagy-related genes in NPM1-mutated leukemia, we first investigated the differentially expressed genes (DEGs) between NPM1-mutated AML cases and NPM1-unmutated AML cases from three public datasets (TCGA, GSE15434, and Beat-AML) and took the intersection of DEGs from three datasets.