Indeed, the immunoblots confirmed the upregulation of FOXO1 and RAG1 in FARSAKD Jeko cells, and overexpression of FARSA in Jeko and REC1 cells reversed their expression levels (Figure 7B), thus supporting another activated tumor-promoting FOXO1-RAG1 signaling in the FARSA-manipulated MCL cells (Figure 7C). This evidence concerns the gene RAG1 and mantle cell lymphoma.