Among them, the miRNAs miR-34b-3p, miR-29a-3p, miR-34c-5p, and miR-29b-3p appear upregulated in PDX5, and one of their possible targets is the oncogene MYCN mRNA, which is highly maintained over the passages, as the original tumor is NMYC-amplified. The gene discussed is MYCN; the disease is neoplasm.