INS and diabetes mellitus: Several MetS definitions, differing in their focus and their diagnostic threshold values, have been proposed by different international organizations, such as the World Health Organization (WHO) [2], the European Group for the study of Insulin Resistance (EGIR) [3], the National Cholesterol Education Programme Adult Treatment Panel III (NCEP ATP III) [4], the American Association of Clinical Endocrinologists (AACE) [5], the International Diabetes Federation (IDF) [6], and the American Heart Association/National Heart, Lung, and Blood Institute [7] (Table 1).