Specifically, abnormal accumulation of pro-inflammatory cytokines, such as interleukins (IL)-1β [77], IL-6 [78], and transforming growth factor beta (TGF-β) [79], has been described surrounding the amyloid plaques of Alzheimer’s disease (AD) patients, as well as in serum and plasma of patients affected by neuropsychiatric disorder [80]. Here, IL1B is linked to Alzheimer disease.