The EBV induces autoimmunity in the pSS through multiple proposed mechanisms, including molecular mimicry and cross reactivity between the viral EBNA-2 protein and Ro-60 antigen, as well as EBER-1 and EBER-2 viral proteins and La antigens, that trigger autoreactive B or T cells [17]. The gene discussed is SSB; the disease is Autoimmunity.