Figure 4H shows the risk of the respective patient groups as regards having lymph node involvement and clearly visualizes that a loss of C/EBPβ in addition to low C/EBPδ results in a significantly increased risk of having tumor cell-positive lymph nodes (risk = 1 vs. 0.6 for C/EBPδhigh-patients). The gene discussed is CEBPD; the disease is neoplasm.