The aim of this study was to evaluate whether three major C/EBP-members act redundantly in PDAC and whether the quantification of C/EBPβ and/or C/EBPγ, in addition to C/EBPδ protein expression, in primary tumor tissue of PDAC patients might refine the prediction of patient survival or the likelihood of lymph node involvement. This evidence concerns the gene CEBPD and neoplasm.