The authors used an IL-10−/− murine model of AD established by epicutaneous sensitization with OVA on tape-stripped-skin and reported a decrease in eosinophil infiltration, a reduced expression of eotaxin (an eosinophil chemoattractant), IL-4, and IL-5 in the OVA-sensitized skin sites of these animals [124]. The gene discussed is IL4; the disease is Alzheimer disease.