Although HEBP2 and SLC25A37 have been described to be involved in different diseases such as cancer [78,79,80,81,82,83], anemia [84,85], porphyria [70,86], or depression [87], we focused on TFAM for further studies due to its widely observed implication in different neurodegenerative disorders, PD being among them. This evidence concerns the gene TFAM and major depressive disorder.