ABCA7 and Alzheimer disease: Among them, the expression of gene Abca7 (ATP-binding cassette subfamily A member 7), which is now considered an important genetic determinant of late-onset AD [27], was lower in OXYS rats in both brain regions and at both ages (log2fold change = −0.56; Padj = 6.53 × 10−5 for PFC at P3; log2fold change = −0.39, Padj = 2.33 × 10−4 for hippocampus at P3; log2fold change = −0.52, Padj = 9.07 × 10−4 for PFC at P10; log2fold change = −0.21, Padj = 2.11 × 10−3 for hippocampus at P10).