L1CAM and glioblastoma: Of the 44 pathways derived from overexpressed genes in normal vs. GBM, only 4 pathways (FDR < 0.1) intersected with the contrasts: ion homeostasis (a); interaction between L1 and Ankyrins (b); unblocking of NMDA receptors, glutamate binding and activation, and L1CAM interactions (e).