Of 28 antigens present in the axon guidance pathway, 9 (DPYSL2, UBB, MYH10, USP33, ANK3, SPTAN1, SH3GL2, ITSN1 and AP2M1) were overexpressed in healthy individuals, and 13 (GPC1, RPL36A, RPS9, RPS2, ROBO3, RPL27, MYL6, RPS15, RPS18, TUBA1A, RPL13, RPS21 and ACTG1) were overexpressed in GBM tissue. The gene discussed is ROBO3; the disease is glioblastoma.