SETD4 and cancer: Figure 3B shows the p-value of the co-expression of SETD4 and PRDM15 across different cancer types, and a great significance is observed among many cancer cell lines. The expression of other genes that were predicted to be associated with PRDM15 were analyzed further based on the Lineage subtype and subsubtype. SETD4 and CDCD2 stand out as two genes which have the strongest co-expression profiles (Figure 3C,D).