Concerning CPT1a, which induces fatty acid oxidation and autophagy in the liver [53], the negative association with the hepatic expression of ATG7, one of the main mediators of autophagy, is logical since autophagy was found to be increased in our NASH patients, the stage when fatty acid oxidation might be inhibited [54]. Here, CPT1A is linked to metabolic dysfunction-associated steatohepatitis.