To investigate whether CD96 is involved in the immune infiltration process of pan-cancer, the ESTIMATE algorithm can be used to evaluate the proportion of stromal cells in tumor microenvironment (TME), the proportion of immune cells in TME and the combined proportion of the above two cells in TME in each sample, using the Stromalscore, Immunescore, and Estimatescore algorithms, respectively. This evidence concerns the gene CD96 and cancer.