The frequencies of CD4 rs1922452, CD4 rs951818, and LAG3 rs870849 genotypes and allelic variants, that were in Hardy–Weinberg’s equilibrium, both in migraine patients and in healthy controls groups, did not differ significantly between the two groups, both considering the whole group (Table 1), and when analyzing each sex separately (Supplementary Table S1). This evidence concerns the gene LAG3 and migraine disorder.