TPM2 and cancer: Transcripts that encoded the tumor suppressors NDGR1 and RIP4 were decreased and transcripts that encoded the tumor-promoting proteins GDNF, ZNF22 and ANXA3 were increased in Δ133p53 cells, particularly Δ133p53β, which is consistent with a role for Δ133p53β in promoting cancer; however, some results were inconsistent with a role for Δ133p53β in promoting cancer, with increased expression of the tumor suppressor TPM2 and decreased expression of SOX9, which was described as having both tumor suppressor and tumor-promoting properties [11,12,13,14,15,16,17,18].