The hepatic mRNA levels of Cspg4 were drastically increased from 7 days after feeding a methionine-choline-deficient and high fat (MCDHF) diet and continued to increase in a way correlated with the progression of liver fibrosis, with a maximal increase (31.24 fold) at 28 days after feeding an MCDHF diet (Figure 1B). Here, CSPG4 is linked to Hepatic fibrosis.