TP53 and systemic lupus erythematosus: The results illustrated that upregulated DEGs were enriched in pathways related to systemic lupus erythematosus, p53 signaling, FoxO signaling, and ribosomes (Figure 1F); pathways associated with DNA replication, cell cycle, mismatch repair, glycolysis/gluconeogenesis, and metabolism were significantly overrepresented in suppressed DEGs (Figure 1G).