It was found that pregnancies with fetal growth restriction, preeclampsia or HELLP, and preeclampsia or HELLP and fetal growth restriction showed significantly lower values of PlGF and a higher sFlt-1/PlGF ratio than control pregnancies in both groups with different gestational age: before and after 34 weeks (Table 9 and Table 10). Here, PGF is linked to fetal growth restriction.