To explore whether CPT1C-mediated lipidome changes, as described in the literature [22], could affect the composition of PM in BC cells, we selected the MDA-MB-231 cell line as a model of TNBC [30], and inhibited CPT1C using two short-hairpin (sh) RNAs: shCPT1C_1 and shCPT1C_2 (Figure 1A). The gene discussed is CPT1C; the disease is breast cancer.