IL6 and idiopathic pulmonary fibrosis: These results confirmed the pivotal role of the lipid metabolism and inflammation in the pathogenesis of IPF, as already found by Landi et al. in 2014 and 2020 [2,26], while LC-IPF up-regulated proteins are mainly related to inflammation by IL-6 signaling, cell adhesion and regulation of cytoskeleton rearrangement, retinoic acid regulation, and its role in the initiation of transcription.