A meta-analysis was performed to underline the effects of different exercise interventions on bone metabolism biomarkers of non-metastatic BC patients, showing an overall significant MD% decrease in NTX serum level [ES: −11.65 (−21.13, −2.17), p = 0.02)] and an increase in BSAP levels [ES: +6.09 (1.56, 10.62), p = 0.008)]. Here, PAX5 is linked to breast cancer.