Desamero et al. [46] used A4gnt KO mice, which display full-blown differentiated-type gastric adenocarcinoma, because the A4gnt gene (that encoding for α1 glycosyltransferase) deletion induces the complete loss of αGlcNAc (α1, 4-linked N-acetylglucosamine residues) expression, producing the progressive development of differentiated-type gastric adenocarcinoma confined in the pyloric mucosa of mutant mice. The gene discussed is A4GNT; the disease is gastric adenocarcinoma.