The anticarcinogenic mechanism of the diterpenes could be explained by the fact that they bind to proteins that play a role in cancer cell growth, including the Kirsten rat sarcoma viral oncogene homolog (K-RAS), pyruvate kinase M2, peroxisome proliferator-activated receptor delta, tubulin, phospholipase A2, and vascular endothelial growth factor receptor 2. The gene discussed is KRAS; the disease is cancer.